Dec 26 2024
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Endocrinology and Metabolism Research Center

Tehran University of Medical Sciences

Short Stature

Short Stature: Genetic and Hormonal Causes

Short Stature

Short stature, also known as dwarfism, is a condition characterized by significantly reduced height compared to the general population. Typically, an adult shorter than 147 centimeters is considered to have short stature. However, the average height among individuals with dwarfism is approximately 122 centimeters.
Types of Short Stature:
 * Proportional dwarfism: Individuals with proportional dwarfism have body proportions that are relatively normal, but their overall size is reduced. This condition is often associated with hormonal imbalances and may be treatable with growth hormone therapy.
 * Disproportionate dwarfism: In this type, body proportions are uneven. For instance, in achondroplasia, a common form of disproportionate dwarfism, the arms and legs are shorter than the torso.
Causes of Short Stature:
Over 300 genetic conditions can lead to short stature. Some of the most common causes include:
 * Achondroplasia: A genetic disorder characterized by short limbs and a relatively large head.
 * Turner syndrome: A chromosomal disorder affecting females, resulting in a variety of health issues, including short stature.
 * Growth hormone deficiency: A condition where the body doesn't produce enough growth hormone, leading to impaired growth.
 * Hypothyroidism: An underactive thyroid gland can disrupt growth and development, particularly in childhood.
Diagnosis:
Diagnosis of short stature typically involves a physical examination, a detailed medical history, and various diagnostic tests such as hormone level assessments and X-rays.
Treatment:
Treatment options for short stature depend on the underlying cause. For example, growth hormone therapy can be beneficial for individuals with growth hormone deficiency.
Living with Short Stature:
Individuals with short stature can lead fulfilling lives. However, they may encounter challenges related to accessibility and societal perceptions.
 
 
 
 
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fatemeh zakerhoseini
Author:

fatemeh zakerhoseini

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