Statins are drugs that inhibit the enzyme responsible for making cholesterol, 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoA), which reduces cholesterol synthesis in the liver. This group includes simvastatin, atorstatin, lovastatin, etc. Although statins are very effective drugs in reducing blood cholesterol, their negative effects include muscle pain, muscle weakness, and neuropathy in some patients.