Tropones are valuable moieties in the synthesis of natural products and bioactive molecules. Tropones have also emerged as fascinating synthetic partners for various (4 + 2)-, (4 + 6)-, (6 + 3)-, (6 + 4)-, (6 + 6)-, (8 + 2)-, and (8 + 3)-cycloaddition reactions as well as functionalization reactions. This review highlights various cycloaddition and functionalization reactions involving tropone building blocks reported since 2014.